LAST UPDATED October 22, 2025

Top Cleaning and Sanitizing Firms in United States

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  • Cardinal Cleaning

    Conyers - United States

    At Cardinal Cleaning, we believe in making a noticeable difference in your home by providing consistent quality and reliable service. We understand how important it is to have a clean environment while respecting your time and handling your possessio

  • Scrub ‘N Bubbles Cleaning Service is family-owned and operated right here in the Treasure Valley. We treat every customer like they are a part of our family. Other companies may offer similar services, but our services come with a personal touch. O

  • Pure Air Ducts

    El Paso - United States

    As a full-service company, our experienced and certified technicians are prepared to support you every step of the way. From diagnosing the problem to fully restoring your property to an even better condition than before, you will have the same profe

  • HomeMaid Cleaning Pro LLC

    Tacoma - United States

    Homemaid provides exceptional commercial cleaning services tailored to your needs. We focus on creating a clean, safe, and healthy work environment for your business, using top-quality products and techniques to ensure every space shines with cleanli

  • Specialty Landscape Inc.

    Fresno - United States

    Expert hardscape patio contractors in Fresno are here to create the perfect outdoor space for you. At Specialty Landscape Inc., we specialize in custom patio designs using high-quality materials like stone, brick, and concrete. Our team ensures your

  • Risk Removal

    Timnath - United States

    Risk Removal is a trusted environmental and specialty cleanup company serving Colorado with a commitment to safety, health, and professionalism. We offer a range of expert services including hoarder cleanup, asbestos roof removal, mold remediation, j

  • All Purpose is your all-in-one solution for top-quality handyman and cleaning services. We proudly extend our services to Orlando and surrounding areas, including Kissimmee, St. Cloud, Lake Nona, Doctor Phillips, Windermere, and beyond. Whether resid

  • At Patriot Maids of Indianapolis, we specialize in delivering meticulous and customized cleaning services to meet your unique requirements. Our professional team ensures every corner is thoroughly cleaned, leaving your space immaculate and inviting.

  • Eco Clean Ellie's

    Lawrence - United States

    Eco Clean Ellie’s is proud to serve Lawrence, KS, and nearby communities with an award-winning team dedicated to excellence. Our skilled professionals bring years of experience and attention to detail to every cleaning project, ensuring your home o

  • Castle Keepers

    Greenville - United States

    "At Castle Keepers House Cleaning, we take great pride in our professionalism. Our cleaning technicians are better screened, better trained, and provide a better clean. Castle Keepers House Cleaning is independently owned, not a franchise."

  • Cleaning and Sanitizing Firms in United States

    Do you want to keep your home or office clean and germ-free? You’ve come to the right place. At SEMFirms, we’ve gathered a list of the top Cleaning & Sanitizing companies that make spaces sparkle and stay healthy. These experts know how to use the best products and techniques to get rid of dust, dirt, and germs. We picked them by looking at how well they clean, how many happy customers they have, and how long they’ve been keeping places neat. We also checked their prices so you know you’re getting value for your money. Reading real feedback from real people helped us see who does the best job every time. We did all this so you can simply choose one and rest easy knowing your space will be safe and spotless.

    Now, let’s explain why these companies made our list. We look at how quickly they show up and finish the job, and if they answer your questions in a friendly way. We check if they use safe, eco-friendly products that won’t harm people or pets. We also make sure they have a good reputation for doing thorough work in homes, offices, or schools. By choosing one of our top picks, you can trust they’ll cover every corner and pay attention to detail. SEMFirms updates this list often, adding new cleaning stars and removing any that don’t meet our standards anymore. That way, you always know you’re picking from the best Cleaning & Sanitizing experts.